Summary
Customization is a core part of what makesWarframeso enjoyable. Hundreds of mods, cosmetic options, and a near-infinite amount of buildskeep players coming backtime and time again.
With the Heart of Deimos update, this level of customization was amplified further by allowing players to apply certain Warframe powers onto any Warframe in the game. Players can use Warcry on melee Warframes, Roar to gain a large damage increase, or use Condemn to gain Shields while chaining targets. In order to use these abilities, however, players will need to obtain the Helminth Segment in the Cambion Drift on Deimos. Here is a complete guide onhow to unlock the Helminth system inWarframe.
Updated on June 21, 2025, by Rhenn Taguiam:With Warframe: 1999 teasing itself as a thrilling sci-fi prequel story that will explore the world of Warframe before the mysteries of its present-day Origin System, fans of the franchise might be eager to wield more archaic weapons while still enjoy ninja-esque thrills in the upcoming story. However, fans of Warframe who want to start fresh orbeginners who are just getting into the gamemight be intrigued as to just how they can unlock certain aspects of the game, such as the Helminth System. As this part of the RPG takes a few questlines before being fully unlocked, players may be interested in learning just how they can fully access Helminth System, especially in the context of more specific steps in these quests and other requirements.
1Complete The Earth To Mars Junction
Setup For Tougher Challenges
Before gamers can evenstart upgrading their Warframesthrough the Helminth, the game ensures that players are equipped enough to do so. As a majority of the prerequisites for the Helminth are located in Deimos, players need to first access the Red Planet’s moon by unlocking the pathway to Mars. This requires completing theEarth to Mars Junction, which is needed to unlock the “Heart of Deimos” quest.
Requirement: Earth to Mars Junction
As players know in theirWarframegameplay, a Junction is a “bridge” that unlocks the pathway from one planet to another celestial body. In the case of the Earth to Mars Junction, players first need to complete the following:
However, before players can even access the Earth to Mars Junction, they need to complete the previous Junctions before it. Their general requirements are the following:
2Start The Heart Of Deimos Quest
Introducing The Entreri
When players finish the Earth to Mars Junction, the player will receive a message from Loid. He is a Cephalon servant to the Entrati, a mysterious Orokin family who have taken residence in the Necralisk. Not much is known about them at that time in the player’s experience, but the resulting comments in-game imply they hold some sort of significance to the lore.
Unlocking Heart Of Deimos
The message states that the Entrati have requested the player’s assistance on their home in Cambion Drift, Deimos. Players need to accept this by heading to theCodexon the Orbiter, located directly across from the Marketplace. They can browse the menu untl they see“The Heart of Deimos,”which they can then unlock to formally begin.
3Reach The Cambion Drift On Deimos
Explore The Brutal Martian Landscape
Players might be surprised to find out that there’s no immediate way of going to the Cambion Drift unless they go to Deimos itself. While there aren’t any Junctions hindering gamers from accessing Deimos from Mars, players do need to explore certain Nodes before unlocking the actual zone.
Within Deimos, players still need to complete specific Nodes to actually unlock the Cambion Drift. These Nodes will give players a general “feel” of the brutal Martian landscape, which, by themselves, are corrupted under Grineer control, with Deimos being an Infested colony.
Unlocking The Cambion Drift
to access the Cambion Drift, players need to complete the following Martian Nodes:
4Complete The Heart Of Deimos Quest
Fix The Entrati Family
Players who finally get to the Cambion Drift will find themselves in the company of Loid, from the inbox message, and the Cephalon Otak who happens to share Loid’s body. They explained that the moon’s Infestation is comprised of a unique Grey Stain, which in turn is threatening to corrupt its very Heart. Not much is expounded about the true origins and role of these terminologies - but to avoid spoilers, they become essential components in the game’s later story arcs.
The rest of the quest involves the player meeting every member of the Entrati family, who they eventually realize arethe heirs to the Albrecht Entrati’s legacy. As lore fans might remember,Albrecht Entratiis known as the Orokin scientist who was the first to discover the Void and its potential. The rest of the quest goes as follows:
Meet Mother
Before players are able to meet Mother in the Necralisk, they have to prove themselves. Players are instructed to:
In the Necralisk, Mother explains that the Heart is the power source of the Void, which in turn provides power to Orokin devices. These include Warframes. Players have to stop the Infestation before it corrupts the Heart, or elsethe Warframes won’t function. Unfortunately, the only person who knows how to help the Heart is Father, who left the Necralisk. Players need to find him.
Find Father
Players venture outside the Necralisk to locate Father. They find a Necramech engaged in battle until its demise. Players eventually find Father in the area, but he doesn’t believe that the Heart is in any danger due to his relationship with Mother. Because of this setback, Loud suggests asking Daughter for help and instructs players to go back to the Necralisk.
Despite this short encounter, players are introduced to theNecramech. This is an Entrati war machine that can be piloted to wreak havoc on the battlefield. In the lore, they were used in the Old War - pertaining to the Orokin’s conflict with the Sentients they created.
Helping Daughter
When players meet Daughter, they are introduced to more of the erratic activities in the Infested landscape of Deimos. Being a family of researchers, it’s no surprise that Daughter is a researcher herself - a biologist, to be exact. She’s only willing to help players if they help rebuild her sample collection in return. Daughter explains that the Cambion Drift occasionally enjoys the presence of two wyrm-like creatures: Fass and Vome. Throughout the day, Vome destroys Fass, which then causesFass Residueto litter the area. Fass regenerates, the siblings fight, and the cycle continues. Daughter asks the player to:
When players return to Daughter, she advises them to go to the Heart and speak with Son and to be wary of him.
Meeting Son
When players go outside the Necralisk, they can find an Esophage that should take them to a cave system. In it lies the door to chamber with the Heart and Son, the exiled Entrati who reveals he was the one who released the Grey Stain in a bid to get his family’s attention.
Unlike the other family members, who gave players some fights and gathering missions to complete, finishing Son’s segment to see the Heart requires completing a puzzle:
After unlocking the Chamber, a pulse temporarily disables the Warframe’s combat systems while a Rogue Necramech opens fire to the Heart. With the Heart damaged, players in the Warframe have depleted Shields and can no longer do any special movement. Players are tasked to avoid the Necroamechs and go back to the surface.
Fighting Back
When players return to the surface, the Entrati convene and realize that they must set aside their differences and work together to restore the Heart. Father returns and provides the player with their ownNecramechtoturn the tide against other Necramechsin the area. Players control this Necramech as they descend and have to do the following:
Defeating the Rogue Necramech will transfer players back to their Warframe. They have to return to the Necralisk to interact with the family.
Happily Ever After
When players go back to the Necralisk, the Entrati family convenes and introduces Grandmother. She says the Entrati will come together in a crisis despite being a dysfunctional family, with the implication being that she caused the events to happen in the first place.
Rewards
Completing the “Heart of Deimos” Quest provides players with the following:
5Obtain Standing With Entrati
Curry Favor With The System’s Best Researchers
It’s specificallyunlocking the Entrati Syndicateand new interactions with the Entrati family that players need in order to properly unlock the Helminth System. Unlike other Syndicates, the Entrati don’t provide Standing through specific activities. Instead,all activities in the Cambion Drift provide Tokens, which can then be redeemed for Standing.
6Reach Associate Rank With The Entrati
A Worthwhile Challenge For The Long-Term Reward
Due to the repetitive nature of some activities in the Cambion Drift, players might feel rather turned off at the notion of even completing them for the Helminth in the first place. However, understanding the overall “cost” of having a better Standing might make the process feel more like a manageable “grand gathering quest.” Here is a list of requirements to achieve Rank 3 with the Entrati:
7Craft And Install Segment Into Helminth Room
Create The Room
Players now have to create the room for the Helminth itself. To do this, they have to acquire the following prerequisites:
8How To Rank Up Helminth
Improve The Helminth With Upgrades
Helminth is similar to the Focus system in that it has unlocks attached to earning experience with it. While Focus is obtained by earning experience for max rank gear,Helminth is upgraded through resourcesand interacting with Warframes.
Experience is earned from feeding Helminth materials, subsuming Warframes, and injecting abilities into Warframes. Feeding Helminth is the fastest way of upgrading it for most veteran players with millions of resources, but newer Mastery Rank 8 players can also receive hefty chunks of experience by subsuming Warframes and injecting said abilities into other Warframes. Subsuming a Warframe grants 160,000 experience while injecting an ability grants 80,000.
